@Joop, to use Gimp on an up to date OS/2 system, you will need to set up a cmd file that puts all the needed DLLs in BEGINLIBPATH and use LIBPATHSTRICT. This is a problem caused by EMX DLLs not being compatible with the rest of the system as OS/2 uses an underline prefix in symbols and EMX doesn't. Shouldn't be hard to do as I did it here. Luckily XFree/86 only needs UNIXROOT set for building.
@Ivan, Snap isolates libraries better then OS/2 is capable of, though we could get close with BEGINLIBPATH, LIBPATHSTRICT and changing PATH. We would still have problems with shared memory that doesn't exist on Linux.
@Doug, YUM/RPM is capable of updating locked DLLs though I noticed some recent fixes for this and just like Warpin, you may have to reboot to actually use the updated DLL. I think you may still have some RPM packages left that was installed along with eCS 2.2b2.
RPM is very fragile is hated everywhere but enterprise uses it and the folks driving development know it.