Hi Jim, my personal experience as average user, having re-joined OS2 Warp 4.52 after 25 years, consists in almost all what described by Martin.
My
2 cents suggestions are:
-with Warp 4.52 go for a VirtualBox guest machine -not real hardware- as it best interfaces to all host peripherals. I read you already thought it
-choose a ready "first run" .vdi file, avoiding complications with media installation issues. Find a good one here:
https://archive.org/details/VMOS2Warp4.52 just needs to be imported in VirtualBox, then run the vm and it works.
-you will enhance the W4.52 guest machine usability by providing the VB Guest Additions for OS2 with the package adapted by Valery Sedletski
ftp://osfree.org/upload/vbox/additions/VBoxAdditions-os2-x86-5.0.51.r218.zip-Software installation/integration will be much more easier than it use to be 25 years ago, if you install ANPM (a packages downloader/installer from repositories) which provides all required dependencies, just same as it works in Linux distributions for software installation. Also WarpIn and InnoTek installers should be considered for the many software packages distributed in that format. Look: WarpIn is required to install ANPM
-Java OpenJDK (version GA 1.6.0) installation will give you the possibility to run a multiplatform and wide choice of recent software packed in .JAR , mostly ready to be executed in a standalone file. Visit
https://joopn.home.xs4all.nl/os2ecs/ecs6e.htm-if you are looking for a free and quick installable Office suite I would suggest Staroffice 5.1 in addition to what Martin mentioned.
I find it still makes a good job especially for wordprocessing and format compatibility