You can just reinstall the YUM/RPM stuff. Should backup your package list first with ANPM, Manage-->Yum Tools-->Export package List.
Basically, go to d:\usr\lib, run unlock *.dll. Move d:\usr, d:\var, d:\etc out of the way, forget if a reboot should be done, I think not. Run ANPM to bootstrap the RPM system. I'd suggest not enabling netlabs-exp at first. You can import your packages or manually install them. Test, eventually enable netlabs-exp and see if things keep working.