Just move it out of the 'Startup' folder then it won't be loaded.
If that is the best solution. In fact this program does not make sense to use it nowadays, because the only thing that it does is to create you a usb printer, if it does not find it. But you can always create it manually.
Also, it is unlikely that usbdrv216 would be the cause of your problem.
No, In my case this driver is the solution to many problems.
The problem that I have, not only happens to me with videos on youtube. Also it happens to me with the wps, specifically if I select the find of the right mouse button on the desktop, and I look for in a unit of 255gb. searching for one file and I tell you to save it in a folder. I have not the problem in a 30gb drive.
I think if wps, has lines of code the same as usbmon.exe, somewhere, can cause this problem.
After the error appears in the wps-finder. To conclude the system, it is the same if I unplug and plug the external USB mouse, that if I turn off and turn on the wifi. This is what allows me to continue the shutdown.